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Panchatikta Ghrita Guggulu

Panchatikta Ghrita Guggulu

Panchatikta Ghrita Guggulu (also called Panchatikta Guggulu Ghrita) is an ayurvedic medicine mainly used for diseases of bone, joints, muscles and skin. It is also used in the treatment of tumor, fistula-in-Ano, abdominal distension, piles, polyuria, tuberculosis, tastelessness, asthma, cervical lymphadenitis & lymphadenopathy, etc.

Ingredients (Composition)

Ingredients Quantity
Azadirachta Indica – Neem (bark) 480 grams
Trichosanthes Dioica – Patola (leaves) 480 grams
Tinospora Cordifolia – Giloy (Guduchi) 480 grams
Adhatoda Vasica – Vasaka 480 grams
Solanum Xanthocarpum – Kantakari 480 grams
Water for decoction 24.456 Kg
The decoction is prepared using above ingredients and reduced to 3.057 Kg liquid. Then filtered and following ingredients are added.
Shuddha Guggulu 240 grams
Cow’s Ghee 768 grams
Now, the mixture is heated and simmered until it becomes thick and then following ingredients are added.
Cyclea Peltata (Cissampelos Pareira) – Patha 12 grams
Embelia Ribes – Vaividang (False Black Pepper) 12 grams
Cedrus Deodara – Devdaru (Deodar Cedar or Himalayan Cedar) 12 grams
Scindapsus Officinalis – Gajpippali 12 grams
Sarjikakshara 12 grams
Yavakshara –  Alkali prepared from Hordeum Vulgare 12 grams
Zingiber Officinale – Sonth (dried ginger root) 12 grams
Curcuma Longa – Turmeric (Haldi) 12 grams
Anethum Graveolens – Soya (Dill) – (Anethum Sowa) 12 grams
Piper Chaba – Chavya (Java Long Pepper) 12 grams
Saussurea Lappa – Kushta 12 grams
Zanthoxylum Armatum (Zanthoxylum Alatum) – Tejovati or Tumbaru (Toothache Tree) 12 grams
Piper Nigrum – Black Pepper (Kali Mirch) 12 grams
Holarrhena Antidysenterica – Indrayava 12 grams
Cuminum Cyminum – Jeera (Cumin Seeds) 12 grams
Plumbago Zeylanica – Chitrak 12 grams
Picrorhiza Kurroa – Kutki 12 grams
Semecarpus Anacardium – Shuddha Bhilawa (Bhallataka) 12 grams
Acorus Calamus – Vacha 12 grams
Piper Longum roots – Piplamool 12 grams
Rubia Cordifolia – Manjistha 12 grams
Aconitum Heterophyllum – Ativisha (Atish) 12 grams
Terminalia Chebula – Haritaki 12 grams
Terminalia Bellirica – Bibhitaki 12 grams
Emblica Officinalis – Amla (Indian Gooseberry) 12 grams
Trachyspermum Ammi – Carom Seeds (Ajwain) 12 grams
Above ingredients are mixed and some manufacturers prepare it in tablet form.
Reference: Bhaishajya Ratnavali, Chapter 54, KUSHT ROG CHIKITSA, Verse: 233 – 236 and Ashtanga Hridayam, Chikitsa Sthana, Chapter 21, Vatavyadhi Chikitsa Adhyaya, Verse: 58 – 61
In Ashtanga Hridayam, all ingredients and their proportion are same, but all ingredients are taken together and cooked to obtain Panchatikta Guggulu Ghrita. It is also called Nimbadi Ghrita and Gulguluthikthakam Ghrita.

Pharmacological Actions

Ingredients in Panchatikta Ghrita Guggulu act on bone, joints, muscles, skin, lymph glands, spine, intestine, nerves, bone marrow, anorectal tissue, heart, blood, lungs, and airways. Therefore, it is useful in diseases related to these organs. Mainly, it is anti-inflammatory, antitoxin, and antipruritic.

Medicinal Properties

  • Antitoxin
  • Antipruritic
  • Demulcent
  • Depurative (purifies blood)
  • Neuroprotective
  • Anti-rheumatic or Anti-arthritic
  • Anti-inflammatory
  • Analgesic
  • Adaptogen
  • Antitumor
  • Anticancer
  • Anti-mutagenic
  • Antiproliferative
  • Antitussive
  • Antiulcerogenic (effects appear in skin diseases)
  • Cardioprotective
  • Carminative
  • Haematinic (increases hemoglobin levels)

Ayurvedic Properties

DOSHA KARMA (Effect on Humors) Pacifies Tridosha (Three Dosha)VATA DOSHA, PITTA DOSHA & KAPHA DOSHA, but mainly beneficial for Vata & Pitta Dosha
Dhatu (Tissue) Effect RASA, RAKTA, ASTHI, MAJJA
Organs Effect Bone, Joints, Muscles, Skin, Lymph Glands, Spine, Intestine, Nerves, Bone Marrow, Anorectal Tissue, Heart, Blood, Lungs and Airways
Main Indication Skin Disorders & Diseases of musculoskeletal system and Nervous system

Therapeutic Indications

Panchatikta Ghrita Guggulu is indicated in following health conditions:

  • Osteoarthritis
  • Diseases of Bone Marrow
  • Fistula
  • Anorectal diseases
  • Fistula-in-Ano
  • Skin diseases – Dermatitis, eczema, psoriasis etc.
  • Abscesses
  • Skin Ulcers
  • Cervical lymphadenitis & lymphadenopathy
  • Tumors or abnormal growths
  • Polyuria
  • Tastelessness
  • Tuberculosis
  • Asthma
  • Cough
  • Sinusitis
  • Edema
  • Cardiac Weakness
  • Anemia
  • Intoxication
  • Gout

Dosage & Administration

The general dosage of Panchatikta Ghrita Guggulu is as follows.
Children 1.5 to 6 grams *
Adults 3 to 12 grams *
Maximum Possible Dosage 24 grams Per Day (in divided doses) **
* Once or Twice a day
** The maximum dosage of Swarna bhasma is a general estimate.
Best Time to Take: On empty stomach in the morning & in Late afternoon or early evening (Don’t eat food 2 hours before and an hour after taking it)

Safety Profile

Panchatikta Ghrita Guggulu is considerably safe and well-tolerated in most individuals when Panchatikta Ghrita Guggulu is taken in the recommended dosage under the supervision of an ayurvedic physician.

Side Effects of Panchatikta Ghrita Guggulu

There are no side effects reported with Panchatikta Ghrita Guggulu.

Pregnancy & Lactation

Panchatikta Ghrita Guggulu should be avoided during pregnancy and lactation because it contains Semecarpus Anacardium.


There are no absolute contraindications for Panchatikta Ghrita Guggulu.

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